Endothelial cell dysfunction: The syndrome in making

Endothelial Progenitor Cell Dysfunction in Polycystic Ovary Syndrome: Implications for The Genesis of Cardiovascular Diseases

endothelial progenitor cell dysfunction in polycystic ovary syndrome: implications for the genesis of cardiovascular diseases

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Syndrome X and endothelial dysfunction.

OBJECTIVE Syndrome X (angina, normal coronary arteriogram and positive exercise test) remains an enigma with unexplained features and apparent conflicts of evidence. The present study addressed whether (i) the Syndrome is characterised by generalised flow-related endothelial dysfunction, (ii) myocardial thallium201 defects reflect myocardial or microvascular dysfunction, (iii) endothelial dysfu...

Endothelial cell dysfunction in preeclampsia.

Preeclampsia is a pregnancy-specific syndrome of hypertension and proteinuria and one of the leading causes of perinatal morbidity and mortality. The pathogenesis of preeclampsia, although not entirely clear, is typically abnormal placental implantation, followed by endothelial dysfunction with subsequently resulting vasospasm, coagulopathy, or changes in capillary permeability; this underscore...

Linking endothelial dysfunction with endothelial cell activation.

The thin layer of cells that lines the interior of blood vessels, known as the endothelium, plays a complex role in vascular biology. The endothelium mediates blood vessel tone, hemostasis, neutrophil recruitment, hormone trafficking, and fluid filtration. Endothelial dysfunction, as defined by a lack of NO, has been linked to a variety of disease states, including atherosclerosis, diabetes mel...